国际足球教练在庆功派对中不幸中毒镖毙命,手上的钻石戒指“粉红豹”也随之失踪。谋杀与失窃案迅速成为关注焦点。破案重任落到总探长德雷福斯(凯文·克莱恩 Kevin Kline 饰)肩上。无奈中,他想到了最佳破案人选——探员杰奎斯•克鲁索(史蒂夫·马丁 Steve Martin 饰)。临危受命的克劳索与总探长指派的木讷探员波顿(让·雷诺 Jean Reno 饰)组合成为一对儿“黄金搭档”。克劳索将教练女友歌坛天后仙妮娅(碧昂丝·诺尔斯 Beyoncé Knowles 饰)列为首要的嫌疑对象,谁知调查时却对她一见倾心。 一路上克劳索遭遇各种勤快,钻石贩子、黑道分子、傲气足球明星、赌场老板、风情女政客,各色人物轮番登场,究竟谁才是名钻大盗?案情的进展一波三折,克劳索该如何按时侦破这桩惊世大案,同时有效提防虎视眈眈的总探长把功劳据为己有?When the coach of the France soccer team is killed by a poisoned dart in the stadium in the end of a game, and his expensive and huge ring with the diamond Pink Panther disappears, the ambitious Chief Insp. Dreyfus assigns the worst police inspector Jacques Clouseau to the case. His intention is to give a diversion to the press, while he uses his best men to chase the killer and thief. He assigns Gendarme Gilbert Ponton to work with Clouseau and inform each step of the investigation. When Clouseau is nominated with honor to the highest prize in France, Dreyfus decides to humiliate Clouseau and take him out of the case. However Clouseau has already solved the mystery.